Naltrexone treatment for prolonged grief disorder: study protocol for a randomized, triple-blinded, placebo-controlled trial

Abstract Background There is a lack of effective pharmacotherapy for prolonged grief disorder (PGD). Evidence suggests that the neurobiology of PGD involves the same circuitry as the reward pathway. Based upon this evidence, we hypothesize that PGD can be conceptualized as a disorder of addiction an...

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Bibliographic Details
Main Authors: James Gang, James Kocsis, Jonathan Avery, Paul K. Maciejewski, Holly G. Prigerson
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-021-05044-8