The effect of strand bias in Illumina short-read sequencing data
<p>Abstract</p> <p>Background</p> <p>When using Illumina high throughput short read data, sometimes the genotype inferred from the positive strand and negative strand are significantly different, with one homozygous and the other heterozygous. This phenomenon is known a...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-11-01
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Series: | BMC Genomics |
Subjects: | |
Online Access: | http://www.biomedcentral.com/1471-2164/13/666 |