Functional regeneration and repair of tendons using biomimetic scaffolds loaded with recombinant periostin

The regeneration of functional tendons remains a clinical challenge. Here the authors develop a biomimetic scaffold loaded with recombinant periostin and demonstrate its functionality in promoting tendon stem/progenitor cell recruitment and tenogenic differentiation, and tendon regeneration in a rat...

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Bibliographic Details
Main Authors: Yu Wang, Shanshan Jin, Dan Luo, Danqing He, Chunyan Shi, Lisha Zhu, Bo Guan, Zixin Li, Ting Zhang, Yanheng Zhou, Cun-Yu Wang, Yan Liu
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21545-1