BK Polyomavirus Evades Innate Immune Sensing by Disrupting the Mitochondrial Network and Promotes Mitophagy

BK Polyomavirus Evades Innate Immune Sensing by Disrupting the Mitochondrial Network and Promotes Mitophagy

Summary: Immune escape contributes to viral persistence, yet little is known about human polyomaviruses. BK-polyomavirus (BKPyV) asymptomatically infects 90% of humans but causes premature allograft failure in kidney transplant patients. Despite virus-specific T cells and neutralizing antibodies, BK...

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Bibliographic Details
Main Authors: Julia Manzetti, Fabian H. Weissbach, Fabrice E. Graf, Gunhild Unterstab, Marion Wernli, Helmut Hopfer, Cinthia B. Drachenberg, Christine Hanssen Rinaldo, Hans H. Hirsch
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:iScience
Subjects:
Biological Sciences
Immunology
Virology
Cell Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220304430

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http://www.sciencedirect.com/science/article/pii/S2589004220304430

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