Large-scale East-Asian eQTL mapping reveals novel candidate genes for LD mapping and the genomic landscape of transcriptional effects of sequence variants.

Profiles of sequence variants that influence gene transcription are very important for understanding mechanisms that affect phenotypic variation and disease susceptibility. Using genotypes at 1.4 million SNPs and a comprehensive transcriptional profile of 15,454 coding genes and 6,113 lincRNA genes...

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Bibliographic Details
Main Authors: Maiko Narahara, Koichiro Higasa, Seiji Nakamura, Yasuharu Tabara, Takahisa Kawaguchi, Miho Ishii, Kenichi Matsubara, Fumihiko Matsuda, Ryo Yamada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4067418?pdf=render