Review of Platensimycin and Platencin: Inhibitors of β-Ketoacyl-acyl Carrier Protein (ACP) Synthase III (FabH)

Review of Platensimycin and Platencin: Inhibitors of β-Ketoacyl-acyl Carrier Protein (ACP) Synthase III (FabH)

Platensimycin and platencin were successively discovered from the strain Streptomyces platensis through systematic screening. These natural products have been defined as promising agents for fighting multidrug resistance in bacteria by targeting type II fatty acid synthesis with slightly different m...

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Bibliographic Details
Main Authors: Ruofeng Shang, Jianping Liang, Yunpeng Yi, Yu Liu, Jiatu Wang
Format: Article
Language:English
Published: MDPI AG 2015-09-01
Series:Molecules
Subjects:
platensimycin
platencin
drug resistance
antibacterial activities
synthesis
analogues
Online Access:http://www.mdpi.com/1420-3049/20/9/16127

Internet

http://www.mdpi.com/1420-3049/20/9/16127

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