Prediction of drug cocktail effects when the number of measurements is limited.

Cocktails of drugs can be more effective than single drugs, because they can potentially work at lower doses and avoid resistance. However, it is impossible to test all drug cocktails drawn from a large set of drugs because of the huge number of combinations. To overcome this combinatorial explosion...

Full description

Bibliographic Details
Main Authors: Anat Zimmer, Avichai Tendler, Itay Katzir, Avi Mayo, Uri Alon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-10-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC5675459?pdf=render