Chronic Peripheral Inflammation Causes a Region-Specific Myeloid Response in the Central Nervous System

Summary: Systemic immune dysregulation contributes to the development of neuropsychiatric and neurodegenerative diseases. The precise effect of chronic peripheral immune stimulation on myeloid cells across anatomical brain regions is unclear. Here, we demonstrate brain-region-specific differences in...

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Bibliographic Details
Main Authors: Patrick Süß, Alana Hoffmann, Tobias Rothe, Zhengyu Ouyang, Wolfgang Baum, Ori Staszewski, Georg Schett, Marco Prinz, Gerhard Krönke, Christopher K. Glass, Jürgen Winkler, Johannes C.M. Schlachetzki
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720302904