Transmission of mitochondrial DNA diseases and ways to prevent them.

Recent reports of strong selection of mitochondrial DNA (mtDNA) during transmission in animal models of mtDNA disease, and of nuclear transfer in both animal models and humans, have important scientific implications. These are directly applicable to the genetic management of mtDNA disease. The risk...

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Bibliographic Details
Main Authors: Joanna Poulton, Marcos R Chiaratti, Flávio V Meirelles, Stephen Kennedy, Dagan Wells, Ian J Holt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2920841?pdf=render