Optimization of HILIC method for the analysis of bisoprolol and its impurities considering uncertainties in peak position

This paper presents the robust optimization of hydrophilic interaction liquid chromatographic method for the analysis of bisoprolol and its impurities A and C. Chemometric strategy is applied for detailed understanding of system's behavior and establishing the mathematical relationship between...

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Bibliographic Details
Main Authors: Rakić Tijana, Jovanović Marko, Tumpa Anja, Jančić-Stojanović Biljana, Medenica Mirjana
Format: Article
Language:srp
Published: Pharmaceutical Association of Serbia, Belgrade, Serbia 2014-01-01
Series:Arhiv za farmaciju
Subjects:
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/0004-1963/2014/0004-19631402095R.pdf