CAR-T Cell Therapy: Mechanism, Management, and Mitigation of Inflammatory Toxicities

Engineered T cell therapies such as chimeric antigen receptor (CAR) expressing T cells (CAR-T cells) have great potential to treat many human diseases; however, inflammatory toxicities associated with these therapies present safety risks and can greatly limit its widespread use. This article briefly...

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Bibliographic Details
Main Authors: Joseph W. Fischer, Nirjal Bhattarai
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
CRS
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.693016/full