Two-stage two-locus models in genome-wide association.
Studies in model organisms suggest that epistasis may play an important role in the etiology of complex diseases and traits in humans. With the era of large-scale genome-wide association studies fast approaching, it is important to quantify whether it will be possible to detect interacting loci usin...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2006-09-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC1570380?pdf=render |