Selection of scFv Antibody Fragments Binding to Human Blood versus Lymphatic Endothelial Surface Antigens by Direct Cell Phage Display.

Selection of scFv Antibody Fragments Binding to Human Blood versus Lymphatic Endothelial Surface Antigens by Direct Cell Phage Display.

The identification of marker molecules specific for blood and lymphatic endothelium may provide new diagnostic tools and identify new targets for therapy of immune, microvascular and cancerous diseases. Here, we used a phage display library expressing human randomized single-chain Fv (scFv) antibodi...

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Bibliographic Details
Main Authors: Thomas Keller, Romana Kalt, Ingrid Raab, Helga Schachner, Corina Mayrhofer, Dontscho Kerjaschki, Brigitte Hantusch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4439027?pdf=render

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http://europepmc.org/articles/PMC4439027?pdf=render

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