A stochastic model for microtubule motors describes the in vivo cytoplasmic transport of human adenovirus.

Cytoplasmic transport of organelles, nucleic acids and proteins on microtubules is usually bidirectional with dynein and kinesin motors mediating the delivery of cargoes in the cytoplasm. Here we combine live cell microscopy, single virus tracking and trajectory segmentation to systematically identi...

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Bibliographic Details
Main Authors: Mattia Gazzola, Christoph J Burckhardt, Basil Bayati, Martin Engelke, Urs F Greber, Petros Koumoutsakos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20041204/pdf/?tool=EBI