Urinary thrombin: a novel marker of glomerular inflammation for the diagnosis of crescentic glomerulonephritis (prospective observational study).

Crescentic glomerulonephritis (CresGN), an uncommon rapidly progressive disease, is characterized by severe glomerular inflammation with fibrin deposition. The lack of specific CresGN biomarkers delays diagnosis and threatens life. Because fibrin deposits in CresGN glomeruli indicate thrombin genera...

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Bibliographic Details
Main Authors: Yasunori Kitamoto, Kenji Arizono, Hiroyoshi Fukui, Kimio Tomita, Hiroshi Kitamura, Yoshio Taguma, Takahisa Imamura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4350840?pdf=render