STRUCTURAL AND DYNAMIC PROPERTIES OF MUTANTS OF THE SOD1 PROTEIN ASSOCIATED WITH AMYOTROPHIC LATERAL SCLEROSIS

STRUCTURAL AND DYNAMIC PROPERTIES OF MUTANTS OF THE SOD1 PROTEIN ASSOCIATED WITH AMYOTROPHIC LATERAL SCLEROSIS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease, which affects motor neurons in the brain and spinal cord and leads to patients’ death. One of the causes of motor neuron degeneration and death is the formation of intracellular protein aggregates formed by a mutant SOD1 protein. Re...

Full description

Bibliographic Details
Main Authors: N. A. Alemasov, N. V. Ivanisenko, V. A. Ivanisenko
Format: Article
Language:English
Published: Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences 2015-01-01
Series:Vavilovskij Žurnal Genetiki i Selekcii
Subjects:
sod1
neurodegenerative diseases
molecular dynamics
hydrogen bonds
prediction
survival time
Online Access:https://vavilov.elpub.ru/jour/article/view/322

Internet

https://vavilov.elpub.ru/jour/article/view/322

Similar Items