Cell Invasion Dynamics into a Three Dimensional Extracellular Matrix Fibre Network.

The dynamics of filopodia interacting with the surrounding extracellular matrix (ECM) play a key role in various cell-ECM interactions, but their mechanisms of interaction with the ECM in 3D environment remain poorly understood. Based on first principles, here we construct an individual-based, force...

Full description

Bibliographic Details
Main Authors: Min-Cheol Kim, Jordan Whisler, Yaron R Silberberg, Roger D Kamm, H Harry Asada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4593642?pdf=render