Shiga toxin binding to glycolipids and glycans.

Immunologically distinct forms of Shiga toxin (Stx1 and Stx2) display different potencies and disease outcomes, likely due to differences in host cell binding. The glycolipid globotriaosylceramide (Gb3) has been reported to be the receptor for both toxins. While there is considerable data to suggest...

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Bibliographic Details
Main Authors: Karen M Gallegos, Deborah G Conrady, Sayali S Karve, Thusitha S Gunasekera, Andrew B Herr, Alison A Weiss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3278406?pdf=render