Cells of Matter—In Vitro Models for Myotonic Dystrophy

Myotonic dystrophy type 1 (DM1 also known as Steinert disease) is a multisystemic disorder mainly characterized by myotonia, progressive muscle weakness and wasting, cognitive impairments, and cardiac defects. This autosomal dominant disease is caused by the expression of nuclear retained RNAs conta...

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Bibliographic Details
Main Authors: Magdalena Matloka, Arnaud F. Klein, Frédérique Rau, Denis Furling
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Neurology
Subjects:
dm1
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00361/full