Essential Notes Regarding the Design of Functional siRNAs for Efficient Mammalian RNAi

Short interfering RNAs (siRNAs) are widely used to bring about RNA interference (RNAi) in mammalian cells. Numerous siRNAs may be designed for any target gene though most of which would be incapable of efficiently inducing mammalian RNAi. Certain highly functional siRNAs designed for knockout of a p...

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Bibliographic Details
Main Authors: Kumiko Ui-Tei, Yuki Naito, Kaoru Saigo
Format: Article
Language:English
Published: Hindawi Limited 2006-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/JBB/2006/65052