Essential Notes Regarding the Design of Functional siRNAs for Efficient Mammalian RNAi
Short interfering RNAs (siRNAs) are widely used to bring about RNA interference (RNAi) in mammalian cells. Numerous siRNAs may be designed for any target gene though most of which would be incapable of efficiently inducing mammalian RNAi. Certain highly functional siRNAs designed for knockout of a p...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2006-01-01
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Series: | Journal of Biomedicine and Biotechnology |
Online Access: | http://dx.doi.org/10.1155/JBB/2006/65052 |