THE EFFECTS OF GABA-ERGIC DRUGS ON NALOXONE-PRECIPITATED WITHDRAWAL SIGNS IN CHRONICALLYMORPHINE-TREATED MICE
1) Chronic administration of morphine hydrochloride in the drinking water of mice induced physical dependence. Jumping and diarrhea, two signs of withdrawal, were produced by intraperitoneal (IP) injection of naloxone. 2) Baclofen, bicuculline and picrotoxin decreased the number of mice's jumpi...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tehran University of Medical Sciences
1994-06-01
|
| Series: | Acta Medica Iranica |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/240 |