Modulated Expression of the Protein Kinase GSK3 in Motor and Dopaminergic Neurons Increases Female Lifespan in Drosophila melanogaster

Modulated Expression of the Protein Kinase GSK3 in Motor and Dopaminergic Neurons Increases Female Lifespan in Drosophila melanogaster

Most eukaryotic genes express multiple transcripts and proteins, and a sophisticated gene expression strategy plays a crucial role in ensuring the cell-specificity of genetic information and the correctness of phenotypes. The Drosophila melanogaster gene shaggy encodes several isoforms of the conser...

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Bibliographic Details
Main Authors: Mikhail V. Trostnikov, Ekaterina R. Veselkina, Anna V. Krementsova, Stepan V. Boldyrev, Natalia V. Roshina, Elena G. Pasyukova
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Genetics
Subjects:
glycogen syntase kinase 3
transcription
lifespan
motor neurons
dopaminergic neurons
Drosophila melanogaster
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00668/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2020.00668/full

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