HIV infects astrocytes in vivo and egresses from the brain to the periphery.
HIV invades the brain during acute infection. Yet, it is unknown whether long-lived infected brain cells release productive virus that can egress from the brain to re-seed peripheral organs. This understanding has significant implication for the brain as a reservoir for HIV and most importantly HIV...
Main Authors: | Victoria Lutgen, Srinivas D Narasipura, Hannah J Barbian, Maureen Richards, Jennillee Wallace, Roshanak Razmpour, Tetyana Buzhdygan, Servio H Ramirez, Lisa Prevedel, Eliseo A Eugenin, Lena Al-Harthi |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-06-01
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Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.1008381 |
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