HIV infects astrocytes in vivo and egresses from the brain to the periphery.

HIV infects astrocytes in vivo and egresses from the brain to the periphery.

HIV invades the brain during acute infection. Yet, it is unknown whether long-lived infected brain cells release productive virus that can egress from the brain to re-seed peripheral organs. This understanding has significant implication for the brain as a reservoir for HIV and most importantly HIV...

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Bibliographic Details
Main Authors: Victoria Lutgen, Srinivas D Narasipura, Hannah J Barbian, Maureen Richards, Jennillee Wallace, Roshanak Razmpour, Tetyana Buzhdygan, Servio H Ramirez, Lisa Prevedel, Eliseo A Eugenin, Lena Al-Harthi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008381

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https://doi.org/10.1371/journal.ppat.1008381

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