Transcriptional regulation of the beta-synuclein 5'-promoter metal response element by metal transcription factor-1.
The progression of many human neurodegenerative disorders is associated with an accumulation of alpha-synuclein. Alpha-synuclein belongs to the homologous synuclein family, which includes beta-synuclein. It has been proposed that beta-synuclein may be a natural regulator of alpha-synuclein. Therefor...
Main Authors: | Patrick C McHugh, Josephine A Wright, David R Brown |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3046239?pdf=render |
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