Gene fragmentation in bacterial draft genomes: extent, consequences and mitigation

<p/> <p>Background</p> <p>Ongoing technological advances in genome sequencing are allowing bacterial genomes to be sequenced at ever-lower cost. However, nearly all of these new techniques concomitantly decrease genome quality, primarily due to the inability of their relative...

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Bibliographic Details
Main Authors: Klassen Jonathan L, Currie Cameron R
Format: Article
Language:English
Published: BMC 2012-01-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/13/14