Plasma transferrin and hemopexin are associated with altered Aβ uptake and cognitive decline in Alzheimer’s disease pathology

Plasma transferrin and hemopexin are associated with altered Aβ uptake and cognitive decline in Alzheimer’s disease pathology

Abstract Background Heme and iron homeostasis is perturbed in Alzheimer’s disease (AD); therefore, the aim of the study was to examine the levels and association of heme with iron-binding plasma proteins in cognitively normal (CN), mild cognitive impairment (MCI), and AD individuals from the Austral...

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Main Authors: Azhaar Ashraf, Nicholas J. Ashton, Pratishtha Chatterjee, Kathryn Goozee, Kaikai Shen, Jurgen Fripp, David Ames, Christopher Rowe, Colin L. Masters, Victor Villemagne, Abdul Hye, Ralph N. Martins, Po-Wah So, AIBL
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Cognitively normal
Cognitive impairment
Heme
Hemoglobin
Iron
Online Access:http://link.springer.com/article/10.1186/s13195-020-00634-1

Internet

http://link.springer.com/article/10.1186/s13195-020-00634-1

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