Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib

<p>Abstract</p> <p>Background</p> <p>Several proteins that promote angiogenesis are overexpressed in hepatocellular carcinoma (HCC) and have been implicated in disease pathogenesis. Sunitinib has antiangiogenic activity and is an oral multitargeted inhibitor of vascular...

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Bibliographic Details
Main Authors: Lim Ho Y, Douillard Jean-Yves, Boucher Eveline, Cheng Ann-Lii, Raymond Eric, DePrimo Samuel E, Harmon Charles S, Kim Jun S, Lechuga Maria, Lanzalone Silvana, Lin Xun, Faivre Sandrine
Format: Article
Language:English
Published: BMC 2011-07-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/1/120