Discovery and characterization of the evolution, variation and functions of diversity-generating retroelements using thousands of genomes and metagenomes

Discovery and characterization of the evolution, variation and functions of diversity-generating retroelements using thousands of genomes and metagenomes

Abstract Background Diversity-generating retroelements (DGRs) are a unique family of retroelements that generate sequence diversity of DNA to benefit their hosts by introducing variations and accelerating the evolution of target proteins. They exist widely in bacteria, archaea, phage and plasmid. Ho...

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Bibliographic Details
Main Authors: Fazhe Yan, Xuelin Yu, Zhongqu Duan, Jinyuan Lu, Ben Jia, Yuyang Qiao, Chen Sun, Chaochun Wei
Format: Article
Language:English
Published: BMC 2019-07-01
Series:BMC Genomics
Subjects:
DGR
Metagenome
Cassette structure
DGR sequence diversity
Adenine-specific mutations
Target gene
Online Access:http://link.springer.com/article/10.1186/s12864-019-5951-3

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http://link.springer.com/article/10.1186/s12864-019-5951-3

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