The SIRT3 and SIRT6 Promote Prostate Cancer Progression by Inhibiting Necroptosis-Mediated Innate Immune Response

The sirtuins (SIRTs), including seven family members, belong to class III histone deacetylase (HDAC) enzymes, which have been intensively investigated in cancers. Although the function of SIRTs in the cancer immunology is explored, SIRT-specific mechanisms regulating necroptosis-related innate immun...

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Bibliographic Details
Main Authors: Weiwei Fu, Hong Li, Haiyang Fu, Shuchao Zhao, Weiping Shi, Mengqi Sun, Yujun Li
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2020/8820355