Lack of Pannexin 1 Alters Synaptic GluN2 Subunit Composition and Spatial Reversal Learning in Mice

Lack of Pannexin 1 Alters Synaptic GluN2 Subunit Composition and Spatial Reversal Learning in Mice

Long-term potentiation (LTP) and long-term depression (LTD) are two forms of synaptic plasticity that have been considered as the cellular substrate of memory formation. Although LTP has received considerable more attention, recent evidences indicate that LTD plays also important roles in the acquis...

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Bibliographic Details
Main Authors: Ivana Gajardo, Claudia S. Salazar, Daniela Lopez-Espíndola, Carolina Estay, Carolina Flores-Muñoz, Claudio Elgueta, Arlek M. Gonzalez-Jamett, Agustín D. Martínez, Pablo Muñoz, Álvaro O. Ardiles
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Pannexin 1
long-term depression
GluN2 subunits
behavioral flexibility
synaptic plasticity
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2018.00114/full

Internet

http://journal.frontiersin.org/article/10.3389/fnmol.2018.00114/full

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