Mathematical Models for Quantitative Assessment of Bioluminescence Resonance Energy Transfer (BRET): Application to Seven Transmembrane Receptors (7TMRs) Oligomerization

The idea that seven transmembrane receptors (7TMRs; also designated G-protein coupled receptors (GPCRs)) might form dimers or higher order oligomeric complexes was formulated more than 20 years ago and has been intensively studied since then. In the last decade, bioluminescence resonance energy tran...

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Bibliographic Details
Main Authors: Luka eDrinovec, Valentina eKubale, Jane eNøhr Larsen, Milka eVrecl
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2012.00104/full