Drugs Commonly Applied to Kidney Patients May Compromise Renal Tubular Uremic Toxins Excretion

Drugs Commonly Applied to Kidney Patients May Compromise Renal Tubular Uremic Toxins Excretion

In chronic kidney disease (CKD), the secretion of uremic toxins is compromised leading to their accumulation in blood, which contributes to uremic complications, in particular cardiovascular disease. Organic anion transporters (OATs) are involved in the tubular secretion of protein-bound uremic toxi...

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Bibliographic Details
Main Authors: Silvia M. Mihaila, João Faria, Maurice F. J. Stefens, Dimitrios Stamatialis, Marianne C. Verhaar, Karin G. F. Gerritsen, Rosalinde Masereeuw
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Toxins
Subjects:
protein-bound uremic toxins
chronic kidney disease management
drug-toxin interaction
OAT1-mediated transport
Online Access:https://www.mdpi.com/2072-6651/12/6/391

Internet

https://www.mdpi.com/2072-6651/12/6/391

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