In Vivo Secretion of Bispecific Antibodies Recruiting Lymphocytic Effector Cells

In Vivo Secretion of Bispecific Antibodies Recruiting Lymphocytic Effector Cells

Engineered Fc-lacking bispecific antibodies have shown an exceptionally high potency for recruiting lymphocyte effector cells and enhancing antitumor activity, which is under evaluation in several clinical trials. However, current treatment regimens raise some issues that should be considered, such...

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Bibliographic Details
Main Authors: Luis Alvarez-Vallina, Laura Sanz, Natalia Nuñez-Prado, Marta Compte
Format: Article
Language:English
Published: MDPI AG 2013-06-01
Series:Antibodies
Subjects:
bispecific antibodies
in vivo secretion
gene therapy
cell-based therapy
immunotherapeutic organoids
immunotherapeutic neovessels
Online Access:http://www.mdpi.com/2073-4468/2/3/415

Internet

http://www.mdpi.com/2073-4468/2/3/415

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