Expression of Ki-67 and P16 INK4a in chemically-induced perioral squamous cell carcinomas in mice.

Expression of Ki-67 and P16 INK4a in chemically-induced perioral squamous cell carcinomas in mice.

ABSTRACT Objective: to evaluate the influence of Ki-67 and P16INK4a proteins immunohistochemical expressions on the clinical and morphological parameters of perioral squamous cell carcinoma induced with 9,10-dimethyl-1,2-benzanthracene (DMBA) in mice. Methods: we topically induced the lesions in t...

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Bibliographic Details
Main Authors: Ângela Valéria Farias Alves, Danielle Rodrigues Ribeiro, Sonia Oliveira Lima, Francisco Prado Reis, Andréa Ferreira Soares, Margarete Zanardo Gomes, Ricardo Luiz Cavalcanti de Albuquerque Júnior
Format: Article
Language:English
Published: Colégio Brasileiro de Cirurgiões
Series:Revista do Colégio Brasileiro de Cirurgiões
Subjects:
Carcinogenesis
9,10-Dimetil-1,2-benzanthracene
Immunohistochemistry
Ki-67 Antigen
Genes, p16
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912016000200072&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912016000200072&lng=en&tlng=en

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