Urethral Catheter Biofilms Reveal Plasticity in Bacterial Composition and Metabolism and Withstand Host Immune Defenses in Hypoxic Environment

Urethral Catheter Biofilms Reveal Plasticity in Bacterial Composition and Metabolism and Withstand Host Immune Defenses in Hypoxic Environment

Biofilms composed of multiple microorganisms colonize the surfaces of indwelling urethral catheters that are used serially by neurogenic bladder patients and cause chronic infections. Well-adapted pathogens in this niche are Escherichia coli, Proteus, and Enterococcus spp., species that cycle throug...

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Bibliographic Details
Main Authors: Yanbao Yu, Harinder Singh, Tamara Tsitrin, Shiferaw Bekele, Yi-Han Lin, Patricia Sikorski, Kelvin J. Moncera, Manolito G. Torralba, Lisa Morrow, Randall Wolcott, Karen E. Nelson, Rembert Pieper
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Medicine
Subjects:
proteomics
catheter biofilm
infection
bacterial metabolism
pathogen
polymicrobial
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.667462/full

Internet

https://www.frontiersin.org/articles/10.3389/fmed.2021.667462/full

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