Mondo-Mlx Mediates Organismal Sugar Sensing through the Gli-Similar Transcription Factor Sugarbabe

The ChREBP/Mondo-Mlx transcription factors are activated by sugars and are essential for sugar tolerance. They promote the conversion of sugars to lipids, but beyond this, their physiological roles are insufficiently understood. Here, we demonstrate that in an organism-wide setting in Drosophila, Mo...

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Main Authors: Jaakko Mattila, Essi Havula, Erja Suominen, Mari Teesalu, Ida Surakka, Riikka Hynynen, Helena Kilpinen, Juho Väänänen, Iiris Hovatta, Reijo Käkelä, Samuli Ripatti, Thomas Sandmann, Ville Hietakangas
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715009948