Low Expression of miR-448 Induces EMT and Promotes Invasion by Regulating ROCK2 in Hepatocellular Carcinoma

Background/Aims: miR-448 has been reported to exhibit abnormal expression in hepatocellular carcinoma (HCC), however, the essential role of miR-448 in HCC progression is still unclear. Methods: real-time PCR was used to detect the expression of miRNAs and candidate genes in HCC samples (n=117). miR-...

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Bibliographic Details
Main Authors: Huaqiang Zhu, Xu Zhou, Chaoqun Ma, Hong Chang, Hongguang Li, Fangfeng Liu, Jun Lu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
HCC
EMT
Online Access:http://www.karger.com/Article/FullText/430114