Acute Promyelocytic Leukemia: A Constellation of Molecular Events around a Single <i>PML-RARA</i> Fusion Gene

Acute Promyelocytic Leukemia: A Constellation of Molecular Events around a Single <i>PML-RARA</i> Fusion Gene

Although acute promyelocytic leukemia (APL) is one of the most characterized forms of acute myeloid leukemia (AML), the molecular mechanisms involved in the development and progression of this disease are still a matter of study. APL is defined by the <i>PML-RARA</i> rearrangement as a c...

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Bibliographic Details
Main Authors: Alessandro Liquori, Mariam Ibañez, Claudia Sargas, Miguel Ángel Sanz, Eva Barragán, José Cervera
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
acute promyelocytic leukemia
apl
ngs
minimal residual disease
mrd
pml-rara
isoform
relapse
splicing
Online Access:https://www.mdpi.com/2072-6694/12/3/624

Internet

https://www.mdpi.com/2072-6694/12/3/624

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