The IL-33 Receptor ST2 Regulates Pulmonary Inflammation and Fibrosis to Bleomycin

The IL-33 Receptor ST2 Regulates Pulmonary Inflammation and Fibrosis to Bleomycin

Idiopathic pulmonary fibrosis is a progressive, devastating, and yet untreatable fibrotic disease of unknown origin. Interleukin-33 (IL-33), an IL-1 family member acts as an alarmin with pro-inflammatory properties when released after stress or cell death. Here, we investigated the role of IL-33 in...

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Bibliographic Details
Main Authors: Manoussa Fanny, Mégane Nascimento, Ludivine Baron, Corinne Schricke, Isabelle Maillet, Myriam Akbal, Nicolas Riteau, Marc Le Bert, Valérie Quesniaux, Bernhard Ryffel, Aurélie Gombault, Sandra Même, William Même, Isabelle Couillin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
bleomycin
lung
inflammation
fibrosis
suppression of tumorigenicity 2
interleukin-33
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01476/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01476/full

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