Rapid determination of aminoglycosides in pharmaceutical preparations by electrospray ionization mass spectrometry

Rapid determination of aminoglycosides in pharmaceutical preparations by electrospray ionization mass spectrometry

Abstract Aminoglycosides are broad-spectrum antibiotics often employed to combat Gram-negative bacterial infections. A technique based on electrospray-ionization mass spectrometry (ESI-MS) was developed for rapid determination of aminoglycosides. This method, which does not require prior chromatogra...

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Bibliographic Details
Main Authors: Freneil B. Jariwala, John A. Hibbs, Iryna Zhuk, Svetlana A. Sukhishvili, Athula B. Attygalle
Format: Article
Language:English
Published: SpringerOpen 2020-01-01
Series:Journal of Analytical Science and Technology
Subjects:
Aminoglycosides
ESI-MS
Quantitative determination
FIA-SIM
Pharmaceutical sample
Online Access:https://doi.org/10.1186/s40543-019-0202-4

Internet

https://doi.org/10.1186/s40543-019-0202-4

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