Adenoma formation following limited ablation of p120-catenin in the mouse intestine.

Adenoma formation following limited ablation of p120-catenin in the mouse intestine.

p120 loss destabilizes E-cadherin and could therefore result in tumor and/or metastasis-promoting activities similar to those caused by E-cadherin downregulation. Previously, we reported that p120 is essential in the intestine for barrier function, epithelial homeostasis and survival. Conditional p1...

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Bibliographic Details
Main Authors: Whitney G Smalley-Freed, Andrey Efimov, Sarah P Short, Peilin Jia, Zhongming Zhao, M Kay Washington, Sylvie Robine, Robert J Coffey, Albert B Reynolds
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3096651?pdf=render

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http://europepmc.org/articles/PMC3096651?pdf=render

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