Seizure-Induced Arc mRNA Expression Thresholds in Rat Hippocampus and Perirhinal Cortex

Seizure-Induced Arc mRNA Expression Thresholds in Rat Hippocampus and Perirhinal Cortex

Immediate-early genes (IEGs) are rapidly and transiently induced following excitatory neuronal activity including maximal electroconvulsive shock treatment (ECT). The rapid RNA response can be blocked by the sodium channel antagonist tetrodotoxin (TTX), without blocking seizures, indicating a role f...

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Bibliographic Details
Main Authors: Monica K. Chawla, Daniel T. Gray, Christie Nguyen, Harshaan Dhaliwal, Marc Zempare, Hiroyuki Okuno, Matthew J. Huentelman, Carol A. Barnes
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Systems Neuroscience
Subjects:
in situ hybridization
calcium plateau potentials
seizures
confocal microscopy
immediate-early genes
Online Access:https://www.frontiersin.org/article/10.3389/fnsys.2018.00053/full

Internet

https://www.frontiersin.org/article/10.3389/fnsys.2018.00053/full

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