Flow Cytometric Measurement of Blood Cells with BCR-ABL1 Fusion Protein in Chronic Myeloid Leukemia

Abstract Chronic myeloid leukemia (CML) is characterized in the majority of cases by a t(9;22)(q34;q11) translocation, also called the Philadelphia chromosome, giving rise to the BCR-ABL1 fusion protein. Current treatment with tyrosine kinase inhibitors is directed against the constitutively active...

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Bibliographic Details
Main Authors: Liza Löf, Linda Arngården, Ulla Olsson-Strömberg, Benjamin Siart, Mattias Jansson, Joakim S. Dahlin, Ingrid Thörn, Lisa Christiansson, Monica Hermansson, Anders Larsson, Erik Ahlstrand, Göran Wålinder, Ola Söderberg, Richard Rosenquist, Ulf Landegren, Masood Kamali-Moghaddam
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00755-y