Probing Angiotensin Converting Enzyme (ACE) Domain-Dependent Inhibition of Onopordia, Isolated from Onopordon acanthium L., Using a Continuous Fluorescent Assay
Background: Somatic ACE is a two-domain protein, C and N which are resulted from gene duplication. Presence of two active sites with particular properties, demonstrates functional significance of each domain. Increased levels of circulating N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP), could be t...
Main Authors: | Niusha Sharifi, Khosro Khajeh, Shabnam Mahernia, Saeed Balalaie, Ghasem Ataie, Raheleh Jahanbani, Massoud Amanlou |
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Format: | Article |
Language: | English |
Published: |
Tabriz University of Medical Sciences
2018-03-01
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Series: | Pharmaceutical Sciences |
Subjects: | |
Online Access: | http://journals.tbzmed.ac.ir/PHARM/Manuscript/PHARM-24-31.pdf |
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