Probing Angiotensin Converting Enzyme (ACE) Domain-Dependent Inhibition of Onopordia, Isolated from Onopordon acanthium L., Using a Continuous Fluorescent Assay

Background: Somatic ACE is a two-domain protein, C and N which are resulted from gene duplication. Presence of two active sites with particular properties, demonstrates functional significance of each domain. Increased levels of circulating N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP), could be t...

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Bibliographic Details
Main Authors: Niusha Sharifi, Khosro Khajeh, Shabnam Mahernia, Saeed Balalaie, Ghasem Ataie, Raheleh Jahanbani, Massoud Amanlou
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2018-03-01
Series:Pharmaceutical Sciences
Subjects:
Online Access:http://journals.tbzmed.ac.ir/PHARM/Manuscript/PHARM-24-31.pdf