The epithelial-mesenchymal transition induced by transcription factor LEF-1 is independent of β-catenin

Transcription factor lymphoid-enhancer–binding factor 1 (LEF-1) is a key molecule in the Wnt/β-catenin signaling pathway. Slug is one of the Wnt/β-catenin target genes and can induce epithelial–mesenchymal transition (EMT). Previously, we have shown that not only wild-type LEF-1 but also LEF-1 lacki...

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Bibliographic Details
Main Authors: Wakako Kobayashi, Masayuki Ozawa
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Biochemistry and Biophysics Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580818300918