INDENO[1,2,3-DE]PHTHALAZIN-3(2H)-ONE AND ITS ANALOGS – SYNTHESIS AND ANTIINFLAMMATORY PROPERTIES

The purpose of this work was design planar polycyclic compounds as inhibitors of kinases, involved in the pro-inflammatory cascade. These compounds can be used as potential hits for the further anti-inflammatory drug design. Dibenzo[cd,g]indazol-6(2H)-one (1) has been shown as a competitive JNK inhi...

Full description

Bibliographic Details
Main Authors: K. V. Bondar, K. О. Klimenko, О. І. Alexandrova, І. А. Kravchenko, I. A. Schepetkin, S. А. Lyakhov
Format: Article
Language:English
Published: Odessa I. I. Mechnikov National University 2016-04-01
Series:Vìsnik Odesʹkogo Nacìonalʹnogo Unìversitetu: Hìmìâ
Subjects:
Online Access:http://heraldchem.onu.edu.ua/article/view/67512