INDENO[1,2,3-DE]PHTHALAZIN-3(2H)-ONE AND ITS ANALOGS – SYNTHESIS AND ANTIINFLAMMATORY PROPERTIES
The purpose of this work was design planar polycyclic compounds as inhibitors of kinases, involved in the pro-inflammatory cascade. These compounds can be used as potential hits for the further anti-inflammatory drug design. Dibenzo[cd,g]indazol-6(2H)-one (1) has been shown as a competitive JNK inhi...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Odessa I. I. Mechnikov National University
2016-04-01
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Series: | Vìsnik Odesʹkogo Nacìonalʹnogo Unìversitetu: Hìmìâ |
Subjects: | |
Online Access: | http://heraldchem.onu.edu.ua/article/view/67512 |