A Small-Molecule Furin Inhibitor Inhibits Cancer Cell Motility and Invasiveness
Furin, a member the proprotein convertase (PC) family, processes inactive precursor proteins to functional proteins within the Golgi/trans-Golgi network secretory pathway. Furin and other PC family members (furin/PCs) activate proteins vital to proper physiological functioning, including growth fac...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2008-04-01
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Series: | Neoplasia: An International Journal for Oncology Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1476558608800504 |