Galanin Receptor 2 Is Involved in Galanin-Induced Analgesic Effect by Activating PKC and CaMKII in the Nucleus Accumbens of Inflammatory Pain Rats

Galanin Receptor 2 Is Involved in Galanin-Induced Analgesic Effect by Activating PKC and CaMKII in the Nucleus Accumbens of Inflammatory Pain Rats

It has been reported that galanin has an analgesic effect via activating galanin receptors (GALRs). This study focused on the involvement of GALR2 in the galanin-induced analgesic effect and its signaling mechanism in the nucleus accumbens (NAc) of inflammatory rats. Animal models were established t...

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Bibliographic Details
Main Authors: Mengnan Li, Xiaomin Zhang, Chongyang Li, Yanan Liu, Shuang Yang, Shilian Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Neuroscience
Subjects:
galanin receptor 2
inflammatory pain
analgesic effect
nucleus accumbens
CaMKII
PKC
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2020.593331/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2020.593331/full

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